A benzoxazole inhibitor of NADH dehydrogenase in Paracoccus denitrificans
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چکیده
منابع مشابه
A novel inhibitor of NADH dehydrogenase in Paracoccus denitrificans.
In [ l ] low concentrations of Tinopal AN, (1,l-bis(3,N-5-dimethylbenzoxazol-2-y1)methine p-toluene sulphonate), which is present in the optical brightener Uvitex AN (Ciba-Geigy Ltd) [2], inhibited the aerobic respiration of Paracoccus denitrificans. Using inverted membrane vesicles of P. denitrifcans [I], this inhibition was shown to occur in the NADH dehydrogenase (EC 1.66.99.3) region of the...
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Methylamine dehydrogenase from Paracoccus denitrificans was purified to homogeneity in two steps from the periplasmic fraction of methylamine-grown cells. The enzyme exhibited a pI value of 4.3 and was composed of two 46,700-dalton subunits and two 15,500-dalton subunits. Each small subunit possessed a covalently bound pyrrolo-quinoline quinone prosthetic group. The amino acid compositions of t...
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Zinc homeostasis is critical for bacterial survival and is mediated largely at the transcriptional level by the regulation of zinc uptake and efflux genes. Here we use RNA-seq to assess transcriptional changes as a result of zinc limitation in the denitrifying bacterium Paracoccus denitrificans. The results identify the differential expression of 147 genes, most of which were upregulated in zin...
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By gel retardation experiments with crude cell extracts of Paracoccus denitrificans it was demonstrated that a protein specifically binds to the promoter of the P. denitrificans recA gene. PCR mutagenesis of the recA promoter showed that the GAACN7GAAC motif is required for the formation of the DNA-protein complex. This protein also binds to the GTTCN7GTTC motif, which is present in the promote...
متن کاملThe terminal oxidases of Paracoccus denitrificans.
Three distinct types of terminal oxidases participate in the aerobic respiratory pathways of Paracoccus denitrificans. Two alternative genes encoding sub unit I of the aa3 -type cytochrome c oxidase have been isolated before, namely ctaDI and ctaDII. Each of these genes can be expressed separately to complement a double mutant (ActaDI, ActaDII), indicating that they are isoforms of subunit I of...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1981
ISSN: 0378-1097
DOI: 10.1016/0378-1097(81)90091-4